Another first from Biotics Research was the concept of Chondro-Protection via supplementation. In the early 1980's, at the request of a cutting-edge chiropractic physician, Biotics research began researching glyucosaminoglycans (GAGs). We soon focused on Chondroitin sulfates (CS), large, heterogeneous biological polymers used by the body to maintain proper elastic integrity within tissues. The chief GAG of cartilage is CS, a repeating disaccharide, specifically glucuronic acid and sulfated N-acetylglucosamine.
Biotics learned that the benefits of CS were enormous. During the repair of injured connective tissue, CS synthesis precedes collagen synthesis and is essential for proper healing. Additionally, CS are structural components of vascular intima, giving strength and elasticity to blood vessels. We also learned that the aging process causes many changes in CS patterns in cartilage. CS are gradually replaced by other GAGs, affecting vascular permeability as well. In addition, the normal synthesis of CS can be inhibited by nutritional deficiencies, and by the use of anti-inflammatory drugs such as corticosteroids, salicylates, gold salts, ibuprofen, phenylbutazone and other NSAIDs. The benefits of Chondroitin sulfate for patients with osteoarthritis have been well documented as have the cardio protective benefits.
Upon determining that high quality Chondroitin sulfates could be readily absorbed, Biotics Research was determined to make Purified Chondroitin Sulfates available to its professional clientele as a dietary supplement. But again, the raw material was not commercially available at that time. As was the case with CoQ10, we would have to produce it ourselves, which we did. And the rest is history. Today, Chondro-protective products containing Chondroitin sulfates and Glucosamine are among the most commonly prescribed products in the industry. But beware! All Chondro-protective products are not created equal. Recent research suggests that a large percentage of Glucosamine and Chondroitin products are not as potent as they claim to be. Biotics Research is the only professional company that has purified Chondroitin sulfate as a raw material and has done clinical studies with Chondroitin sulfate. Biotics Research uses only purified Chondroitin sulfate from commercial sources that meet or exceed NIH standards of purity. With in house laboratory capabilities, chondroprotective agents can be tested and released for manufacturing at Biotics. Many suppliers of Chondroitin sulfate provide materials that assay at 30% purity compared to 100% purity. The result is that many products on the market do not meet label claim. Using standardized chondroprotective agents provides for repeatable clinical outcomes. At Biotics Research Corporation, our testing and manufacturing processes ensure safe and effective products of the highest quality.