Berberine and Blood Sugar
Berberine and Blood Sugar
Berberine has become synonymous with supporting the maintenance of healthy blood sugar levels, as well as having benefits for the gut, brain and heart. A recent article delves into the biological mechanisms of this botanical to confirm its influence on blood sugar.
Although not fully understood, the pathogenesis of Type 2 Diabetes Mellitus (T2DM) seems to stem from both oxidative stress and inflammation. The inflammatory condition may be the result of various kinase and signaling pathways influencing adipocytes and immunocytes to produce interleukin-6 (IL-6) and tumor necrosis factor-α (TNF- α), both involved in the pathogenesis of T2DM. When the nuclear factor-kB (NF-κB) pathway is activated by these cytokines, it may disrupt the insulin signaling pathways and also induce dysfunction of the islets β-cells...
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