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SNPs Involved in Manganese Deficiency

According to a new study, scoliosis, a curvature of the spine, may be linked to the body’s inability to utilize manganese. In this exome-wide association study of 457 severe adolescent idiopathic scoliosis (AIS) cases and 987 controls, they observed “a missense SNP in SLC39A8 (p.Ala391Thr, rs13107325) associated with severe AIS (P = 1.60 × 10−7,…
