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Relative Risk Reporting & Statins
A recent review paper adds to the growing concern over clinical trial data related to the efficacy of statin drugs being reported in a misleading way. The review focuses on the use of relative risk reduction rather than absolute risk reduction with regard to the efficacy of statins in five landmark randomized controlled trials (RCTs)…
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Statins & Vitamin D
In a recent meta-analysis of 9 cohort studies that included a total of nearly 3,000 participants, the relationship between 25-OH vitamin D (25-OHD) plasma levels and statin-associated myopathy was examined, as well as the effect of vitamin D supplementation on statin intolerance. Given that 10-25% of statin users report muscle-associated symptoms, and that over 60%…
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Questioning Statins’ Efficacy
A meta-analysis published recently in JAMA Internal Medicine raises questions about the efficacy of statin drugs with regard to reducing heart attack, stroke, and all-cause mortality. The findings are important because they may have implications for affecting shared decision-making between doctors and patients when it comes to using statin drugs to lower serum cholesterol levels.