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Air Pollution & Dementia
The Lancet Planetary Health has published a systematic review and meta-analysis of studies examining the association between air pollution and incident dementia. This review was intended to summarize all previous reviews, identify specific gaps in data, and incorporate new primary research. It included data from 32 studies and a pooled population of over 26 million…
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Air Pollution, Insulin Resistance, and BMI
In April 2025, JAMA Network Open published the results of a unique long-term cohort study (Meta-Air2) designed to unravel the connections between air pollution, insulin resistance, and body mass index (BMI). Traffic-related air pollutants (TRAP) have previously been associated with an increase in risk for type 2 diabetes, but the mechanism has not been entirely…
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Air Pollution & Aging
A recently proposed stricter regulation of fine particulate matter (PM2.5) by EPA is a step toward significant reductions in morbidity and mortality, supported by many recently published articles that point to a broad range of adverse health consequences linked to air pollution. An analysis previously published in JAMA Network Open indicates that PM2.5 levels are…
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Environmental Pollutants & the Microbiome
In a recently published Frontiers in Medicine review, the bidirectional interactions between environmental toxicants and the gut microbiota were examined, highlighting the complex relationship between the composition of the microbiota and xenobiotic metabolism. Given that for most people the greatest source of exposure to pollutants is via diet and water consumption, the gut microbiota is…
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L-Arginine & Air Pollution
Last year the results of a multinational, prospective cohort study, the Prospective Urban and Rural Epidemiology (PURE) study, were published, detailing the impact of air pollution on cardiovascular disease. Conducted over nearly 20 years and enrolling communities in 21 countries of varying socioeconomic levels, over 150,000 participants were followed for a median of 9.3 years…
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Mitigating the Effect of Air Pollution on Cardiovascular Mortality
A 2018 report published by the National Academy of Sciences, based upon data from 41 cohorts within 16 countries, implicated air pollution (i.e., ambient fine particulate matter (PM2.5)) in the deaths of 8.9 million people in 2015. This parallels the predictions published in the Lancet in 2015, which found ambient PM2.5 to be the 5th…