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Acid Suppression & CVD
Results of a prospective cohort study published in the International Journal of Cardiology add to the evidence suggesting that acid suppression via proton pump inhibition is associated with an increase in the risk for cardiovascular disease. This was a well-known cohort, part of the UK Biobank Study, and included nearly 460,000 participants without cardiovascular disease…
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Egg Consumption & CVD Risk
Over the years, many articles have been published regarding the potential benefits and harms of egg consumption, primarily on cardiovascular disease (CVD) and diabetes risk. There are multiple challenges with interpreting this type of data, including a lack of randomized controlled trials (the majority of the research is observational), significant conflicts of interest, etc., making…
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Physical Activity & CVD Risk
A new study published in the Journal of the American College of Cardiology provides some mechanistic insight into the benefits of physical activity for cardiovascular disease (CVD) risk reduction, helping to explain why some individuals may have larger benefits than others. This study examined records from over 50,000 individuals who completed a survey regarding their…
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Apolipoproteins & CVD
Data supporting the use of apolipoproteins (APOs) in the assessment of chronic disease continues to mount, with a recent analysis published in the American Journal of Clinical Nutrition suggesting that ApoA1 has a protective effect that extends to dying from all causes, including cardiovascular disease and lung cancer, and that ApoB increases the risk for…
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Modifiable Risk Factors & CVD
A paper published recently in The New England Journal of Medicine noted the not-exactly surprising finding that over fifty percent of incident cardiovascular disease and approximately twenty percent of deaths from any cause may be attributable to five modifiable risk factors: body mass index (BMI), systolic blood pressure, non-HDL cholesterol, current smoking, and diabetes.
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The Impact of Sleep on CVD
It is difficult to overestimate the importance of sufficient quality and duration of sleep on nearly every body system, and multiple recent trials emphasize the critical role it plays in cardiovascular health, including implications for causality to both peripheral and coronary artery disease.
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Exploring Cholesterol & CVD
A series of papers published recently in Current Opinion in Endocrinology, Diabetes and Obesity highlights the growing divide between approaches to cardiovascular disease (CVD) that focus on LDL-cholesterol (LDL-C) and clinical observations that are leading researchers and practicing physicians to refocus attention on other factors that may play a bigger role in atherosclerosis and CVD.
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APO Ratio & CVD Risk
Evidence continues to grow for the value of using apolipoprotein levels (apoB and apoA-1) as the best marker for cardiovascular risk, as they have been shown to be closely associated with cardiovascular outcomes over a wide range of ages and over a long period of time, as reported in a recently published Swedish cohort study.…