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Mitochondria & Dietary Fat

Results of an experimental animal study clarifying the role of mitochondria in the processing and transport of dietary lipids were recently published in Nature. The gastrointestinal consequences of impaired mitochondrial function are not well understood, and this study was done to shed light on the specific role played by mitochondria in lipid processing, potentially leading…
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High Fat Diet Alters Gut Physiology

In a study just published in Science, a mouse-model of diet-induced obesity was used to elucidate possible mechanisms by which a high-fat diet can contribute to atherosclerosis. Animals fed a high-fat diet rich in choline had disruptions in mitochondrial bioenergetics in the cells lining the intestinal tract. The subsequent drop in ATP production, as well…


