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Researchers at Yeungnam University in South Korea investigated functional and structural changes in lipoproteins after consumption of policosanol. They analyzed serum parameters in young non-smokers (YN), young smokers (YS), and middle-aged subjects (MN) who consumed policosanol daily (10 mg/day) for 8 weeks. After 8 weeks, systolic blood pressure was significantly lowered from initial levels in…

Researchers conducted a review and meta‑analysis of 11 randomized controlled trials (RTCs) to evaluate the effect of oral magnesium supplementation on plasma C-reactive protein (CRP) concentrations. The analysis was stratified to compare subgroups of populations; those with a baseline plasma CRP values of ≤ 3 and those having CRP values > 3. The difference between…

Proton Pump Inhibitor (PPI) are widely used by millions of people for indications and durations that were never tested or approved, and are available via prescription or as over the counter (OTC) in several countries including the United States. They are often overprescribed, rarely deprescribed, and frequently started inappropriately during a hospital stay. Their use…

In a prospective, randomized, 6-month, 3-arm, double-blind, crossover trial, placebo was compared to Chondroitin Sulfate (800mg/day) and celecoxib (200mg/day). The changes in pain on a Visual Analogue Scale (VAS), and in the Lequesne Index (LI) were assessed as co-primary endpoints. Secondary endpoints of Minimal-Clinically Important Improvement (MCII) and Patient-Acceptable Symptoms State (PASS) were used. 604…

Prolonged intense exercise has been associated with transient suppression of immune function and an increased risk of infections. The catabolism of tryptophan via kynurenine may play an important role. Researchers examined the effect of probiotic supplementation on the incidence of upper respiratory tract infections (URTI) and the metabolism of aromatic amino acids after exhaustive aerobic…

Category:  Press Release

The natural product curcumin has been demonstrated to inhibit numerous targets in prostate epithelial cells with an importance in cancer formation and progression, including transcription factors, receptors, intracellular kinases, cytokines and growth factors. The effect on androgen receptor (AR) and on its target PSA has been demonstrated by several independent investigators using both endogenously expressed…

Intermittent fasting appears to calm inflammation and rescue cognitive function in animals’ brains. The action is associated with “knocking down the quantity of proinflammatory cytokines, elevating levels of brain-derived neurotrophic factor (BDNF), and activating the transcription factor known as NF-κB, which is involved in adaptive stress responses. In addition, BDNF activates PGC-1α, which functions in…

Researchers wishing to study the effect of vitamin D3 supplementation on prenatal depression scores conducted a randomized clinical trial on pregnant women under prenatal care. Participants were 18 years of age or older with a gestational age of 26-28 weeks, no history of mental illness and no pregnancy complications. Participants had a depression score of…

Researchers investigated the association between serum folate levels and amyloid imaging to clarify whether serum folate could be a biomarker for Alzheimer’s disease (AD). They examined the usefulness of a combined assessment of serum folate levels and red blood cell hemoglobin content. Apolipoprotein E (APOE) gene polymorphisms were also assessed. “Serum folate levels and hemoglobin…

Gestational diabetes mellitus (GDM) is an increasing health risk for pregnant women, and Epigallocatechin 3-gallate (EGCG), an extract from Green Tea, is known to benefit the insulin secretory process. Researcher investigated the effect of daily EGCG supplementation on both maternal and neonatal treatment outcomes in GDM-affected pregnancies in a double-blind, randomized controlled trial. 404 pregnant…

Existing profiles of gut microbiome dysbiosis in adult IBD patients are inconsistent among published studied and have not provided identification of microbial signatures for Crohn’s disease (CD) and Ulcerative colitis (UC). Researchers conducted a longitudinal study to compare the fecal microbiome of CD with patients having UC and with non-IBD subjects. A cohort of 2045…

Unmanageable depression poses significant morbidity and mortality, as well as a substantial societal price. In this study young adults (n=33) who were non-responsive to traditional therapy were assessed for abnormalities in their cerebral spinal fluid (CFS) metabolites, plasma and urine. Cerebral folate deficiency was observed to be the most common deficiency (n=12), with these patients…

Lutein is a carotenoid vitamin related to beta-carotene and vitamin A. Many foods are rich in lutein and these include broccoli, spinach, kale, corn, orange, pepper, kiwi fruit, grapes, orange juice, zucchini, and squash. Lutein is often thought of as “the eye vitamin,” as it is most often utilized in the prevention of eye diseases,…

CurcumRx™ supplies an all-natural turmeric complex, providing up to 50% total curcuminoid content, plus turmeric’s 200 othernaturally occurring compounds, including phenolic compounds, sesquiterpenes, sterol, fatty acids and more!  CurcumRx™ utilizes a specialized emulsion technology, concentrating turmeric’s many nutrients and greatly enhancing bioavailability without the use of nanotechnology, including the use of tweens and other surfactants…

Rubidium (Rb) belongs to the elemental group 1A of the periodic table, the same group as lithium, sodium, potassium and hydrogen. It is a naturally occurring mineral in the human body, estimated to contain 400–900 mg Rb. It is projected that on a weekly basis from dietary consumption 15–25 mg of Rb is absorption, while…

Resveratrol (3, 4, 5-trihydroxystilbene), a natural polyphenolic phytoalexin found in grapes, as well as other botanicals such as knotweed. Interest has arisen due to its cardioprotective action on the vasculature, particularly its ability to inhibit formation of new blood vessels, and to facilitate vasorelaxation. However, recent evidence has noted that it may also be beneficial…

Researchers suspect that oral bacteria could be involved in rheumatoid arthritis (RA). In patients with RA, hypercitrullination, an abnormal buildup of citrullinated proteins, triggers the immune system to generate autoantibodies that attack these modified self-proteins, inducing joint-destroying inflammation. Citrullination is a normal, function altering process that changes the structure of proteins. In patients with RA,…

In a study performed by Ghana B., et al. the value of vitamin D supplementation was assessed in patients with chronic low back pain (CLBP). A high prevalence of hypovitaminosis D (50-90%) was observed in the study group, attributed to low dietary intake, skin color, and “changing lifestyle”, despite ample sunlight. The patients (18-75 year…

Complete BioDetoxification addresses issues associated with common underlying health challenges.   Step One focuses on addressing inflammatory responses with a specific diet, sample daily menus and targeted nutrition for digestive support.   Step Two consists of a thorough metabolic cleansing program with a modified diet, sample daily menus and specific nutrition to complete the detox…

Nutri-150™ enables change in the pursuit of optimal health by providing a meal replacement formula that is only 150 calories per serving, low in carbohydrates, high in fiber, and gluten free. With weight management dominating Internet searches (over 20 million searches each month), and the billions of dollars spent on weight loss supplements per year,…

Bio-ADEK-Mulsion™ supplies vitamins A, D3, E and K (as K2 and K1) in a true oil and water emulsion, resulting in enhanced bioavailability and utilization via the lymphatic system. Bio-ADEK-Mulsion™ does not contain “tweens” or surfactants commonly used by others; compounds which may damage cell membranes and result in gut permeability. Each serving of Bio-ADEK-Mulsion™…

In an animal study, sodium butyrate (NaB) was demonstrated to correct gut microbiota imbalance induced by a high fat diet (HFD), while considerably elevating the magnitude of the beneficial bacteria Christensenellaceae, Blautia and Lactobacillus. These bacteria characteristically produce high amounts of butyric acid. Butyrate in turn served to restore the intestinal mucosa damage induced by…

Vitamin E supplementation was previously reported to improve liver histology in patients with nonalcoholic steatohepatitis, which is a manifestation of the metabolic syndrome (MetS). α-tocopherol bioavailability in healthy adults is higher than in those with MetS, thereby suggesting that the latter group has increased requirements. In populations with MetS-associated hepatic dysfunction, impaired α-tocopherol trafficking is…

Compounds that trigger chemical intolerance and sensitivities include sulfites, phenolic compounds (tannins), mold or yeasts (aldehydes), prostaglandins, histamines, tyramines and congeners (chemical residues from fermentation. Metabolism of these compounds takes place in the liver. Nutrigenomics related to genetic polymorphisms of methylation and detoxification dramatically influence liver metabolism of these compounds. ScentArest® supplies key nutrients shown…

Gastric ulcer is one of the most common chronic gastrointestinal [ailments] characterized by a significant defect in the mucosal barrier. Helicobacter pylori (H. pylori) infection and the frequent long term use of non steroidal anti inflammatory drugs are major factors involved in gastric ulcer development. Acid inhibitors and antibiotics are commonly used to treat gastric…

Proton pump inhibitors (PPIs) are among the most commonly prescribed and used drugs worldwide, and have been linked to acute interstitial nephritis. It has been estimated that between 25% and 70% of these prescriptions have no appropriate indication, and the duration of use extends well beyond recommended guidelines. The object of this study was to…

It is well known that vitamin D positively influences human health, but data on its impact on the human gut microbiome are lacking. Researchers conducted a pilot study on sixteen healthy volunteers. They were endoscopically examined to access a total of 7 sites to investigate the effects of oral vitamin D3 supplementation on the human…

Epidemiologic evidence suggest that the use of chondroitin and glucosamine supplements are associated with reduced risk of colorectal cancer (CRC). Researchers evaluated the association between the use of these supplements and the CRC risk in two prospective cohorts: The Nurses’ Health Study and Health Professionals Follow-up Study. Cox proportional hazards regression was used to estimate…

Researchers from 8 institutions in five countries (Egypt, Saudi Arabia, Norway, China and England) participated in a double-blinded, randomized clinical trial of 109 children (ages 3-10) to determine the efficacy of vitamin D3 supplementation in Autism Spectrum Disorder (ASD) patients. Of those participating, 57% had vitamin D deficiency, and 30% had vitamin D insufficiency. These…