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Physical Activity & Alzheimer’s Risk
The journal Alzheimer’s & Dementia has just published an analysis of the effects of physical activity on preclinical risk factors for Alzheimer’s disease (AD) among middle-aged adults at higher risk for its development. Three hundred thirty-seven adults were recruited from a subset of a larger longitudinal cohort, the Alzheimer’s and Families (ALFA) study. Participants were…
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Biological Age & Dementia
The results of a longitudinal prospective study evaluating the association between biological aging and dementia were recently published in Neurology, as well as evidence regarding changes in brain structures that may mediate any connection. The UK Biobank, a prospective longitudinal cohort with over half a million participants, was used to provide data for nearly 281,000…
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CT Scans & Lifetime Health Risk
Results of a model assessing the lifetime risk of cancer caused by the current rate of computed tomography (CT) examinations in the United States were recently published in JAMA Internal Medicine. Despite the clear benefits of CT, the exposure to ionizing radiation increases the risk for cancer, and this analysis tried to quantify the population…
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Diet & Running-Related Injuries
A systematic review and meta-analysis was recently published in the Journal of Science and Medicine In Sport, examining the association between diet and running-related injuries (RRIs). This review of 15 prospective cohort studies included nearly 6,000 adult distance runners (~2400 female), with 9 ultimately included in the meta-analysis. Sex-specific associations were revealed in this analysis;…
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Western Diet, Pregnancy & Neurodevelopmental Health
Data from several cohort studies suggest that a Western dietary pattern during pregnancy is associated with an increase in risk for neurodevelopmental disorders, including both autism and attention-deficit/hyperactivity disorder (ADHD), with the analysis published in Nature Metabolism. The initial prospective cohort was comprised of approximately 600 children (age 10) who were participants in the Copenhagen…
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African-Based vs Western-Based Diet
The results of a randomized and controlled dietary trial, including a multi-omics analysis of immune and metabolic changes associated with switching between a Western-style dietary pattern and a Kilimanjaro heritage-style pattern, were recently published in Nature Medicine. Male non-overweight participants between the ages of 20 to 40 were recruited from one of two cohorts in…
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Collagen Supplements & Tendon Health
The results of a 12-week randomized and double-blind clinical trial, which reported on the effects of resistance exercise in combination with hydrolyzed collagen on tendon health, were recently published in the European Journal of Sport Science. All participants in this small study (only 24 middle-aged recreationally active men) had 2 sessions of high-intensity resistance training…
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Lifestyle Factors & Cardiovascular Events Among Diabetics
BMC Medicine recently published a post hoc analysis of the ADVANCE trial, describing the relationship between healthy lifestyle factors (HLF) and the incidence of both microvascular and macrovascular events, as well as overall mortality, among people with type 2 diabetes (T2D) and a high risk for cardiovascular disease. The ADVANCE (Action in Diabetes and Vascular…
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Menaquinone-7 & Vascular Health
Results of a 1 year randomized and double-blind controlled clinical trial were recently published in Nutrients, describing the effectiveness of a specific form of vitamin K2, menaquinone-7 (MK-7), on vascular stiffness and blood pressure among postmenopausal women. Two-hundred forty-three participants were enrolled, both men and women, but a post-hoc analysis was conducted to specifically compare…
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Ellagic Acid & NAFLD
The results of a randomized, double-blind, placebo-controlled trial investigating the effects of ellagic acid on multiple metabolic markers among people with non-alcoholic fatty liver disease (NAFLD) were recently published in BMC Complementary Medicine and Therapies. This trial enrolled 44 non-obese participants between ages 18 and 55 (mean age ~ 40) diagnosed with NAFLD by hepatic…