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Sodium & BP
Results of a crossover trial were recently published in JAMA Open Network, evaluating the effects of both a high and low-sodium diet on blood pressure (BP) within the same individuals. Two hundred and thirteen participants consumed (prospectively) a high sodium (2.2 g sodium added to their usual diet) or a low sodium (500 mg total…
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ADHD & Dementia
Using data from a prospective cohort study, an association was observed between adult-onset attention-deficit/hyperactivity disorder (ADHD) and an increased risk for dementia later in life, with an analysis recently published in JAMA Network Open. This association was generated using data from a prospective birth cohort comprised of individuals from Israel born between 1933 and 1952,…
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Early Diet & IBD
The journal Gut recently published the results of a prospective cohort study analyzing the association between diet quality, assessed at age 1 and again at age 3, and the subsequent risk for inflammatory bowel disease (IBD) later in life. Comprised of two Scandinavian cohorts, the All Babies in Southeast Sweden (ABIS) Study and The Norwegian…
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Depression & the Microbiome
Results of a small pilot study published in May 2023 in Neuroscience explored connections between the gut microbiome and depression among young adults. Shotgun metagenomic sequencing was performed on stool samples from 40 young adults with major depressive disorder (MDD) and 42 healthy controls, with results controlled for multiple confounders, including demographics, alcohol or cigarette…
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Mitochondria & Dietary Fat
Results of an experimental animal study clarifying the role of mitochondria in the processing and transport of dietary lipids were recently published in Nature. The gastrointestinal consequences of impaired mitochondrial function are not well understood, and this study was done to shed light on the specific role played by mitochondria in lipid processing, potentially leading…
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New Frontier for ALS?
The bioenergetic changes induced by a ketogenic metabolism appear to be beneficial for neurodegenerative conditions. Promising research is being done on ketogenic diets for Alzheimer’s and Parkinson’s diseases, and a paper published recently in Frontiers in Neurology presents encouraging results from a proof-of-concept case study involving a subject with bulbar-onset amyotrophic lateral sclerosis (ALS) who…
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B12 Supplementation & Breast Milk
Results of a randomized and controlled trial were recently published in the American Journal of Clinical Nutrition, providing more detail on the efficacy and timing of B12 supplementation given pre- and postnatally in the human milk (HM) concentration of B12. Pregnant women between 12-27 weeks gestation were recruited for this study from Tanzania, an area…
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Light Exercise Protects Against Childhood Obesity
Results of a study with over 13 years of follow-up were recently published in Nature Communications, detailing many of the associations between physical activity and fat accumulation in children aged 11 to 24. Data from the UK-based Avon Longitudinal Study of Parents and Children (ALSPAC) birth cohort provided a longitudinal analysis of accelerometer-assessed movement and…
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Does Quality Matter with Low Carb Diets?
Researchers from Harvard’s Chan School of Public Health recently published an analysis of the association between low carbohydrate diets (LCDs) and long-term weight control, with a special focus on diet quality. The analysis included 3 well-described prospective cohorts, the Nurses’ Health Study (NHS) and Nurses’ Health Study II (NHSII), and the Health Professionals Follow-up Study…
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Nutrient Support for PCOS
A systematic review and network analysis was recently published in PeerJ, evaluating the randomized clinical trials of various nutritional therapies for women with polycystic ovarian syndrome (PCOS). A total of 41 studies and over 2300 patients were included in the review, with network analysis providing a comparison of the impact of 8 therapies on specific…