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Acid Suppression & Severe Headache
Results of a cross-sectional analysis were recently published in Neurology, Clinical Practice, which suggest an association between the use of acid-suppressing medications and migraine headaches. Self-reported data from the 1999-2004 National Health and Nutrition Examination Survey (NHANES), which included nearly 12,000 adults, found that any type of acid-suppression therapy was associated with a higher risk…
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Keto Diet & Schizophrenia
An interesting pilot study of ketogenic diets for mental illness was published recently in Psychiatry Research. The study was a single-arm trial with 23 subjects with schizophrenia or bipolar disorder plus metabolic abnormalities. Inclusion criteria were diagnosis of one of those conditions and currently taking psychotropic medications, plus being overweight or having obesity (based on…
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Physical Activity & CVD Risk
A new study published in the Journal of the American College of Cardiology provides some mechanistic insight into the benefits of physical activity for cardiovascular disease (CVD) risk reduction, helping to explain why some individuals may have larger benefits than others. This study examined records from over 50,000 individuals who completed a survey regarding their…
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Mediterranean Diet & IBS
The effect of a Mediterranean diet on both gastrointestinal (GI) and psychological symptoms among people with irritable bowel syndrome (IBS) was recently published in Alimentary Pharmacology & Therapeutics. Designed as a pilot study to evaluate the feasibility of the Mediterranean diet (MD) for people with IBS, this was a 6 week unblinded study in which…
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Diabetes Remission & Weight Loss
Results of a large population-based observational cohort study examining the association between weight loss and diabetes remission were recently published in PLOS Medicine. This Hong Kong-based study included more than 37,000 people recently diagnosed with type 2 diabetes who were followed for a median of 8 years, with a focus on their 1-year weight change…
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Omega-3s & Pregnancy
A report on the intake of fish and omega-3 fatty acids among pregnant women in the U.S. was recently published in Public Health Nutrition. This analysis included 23 cohorts that provided data on fish consumption and 35 cohorts with data on supplement use, together comprising the Environmental Influences on Child Health Outcomes (ECHO) consortium.
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Sleep & Diabetes Risk
JAMA Network Open recently published the results of a large cohort study that assessed the influence of sleep duration on diabetes type 2 risk, as well as any potential modification of that risk by dietary habits. A previous meta-analysis published in Diabetes Care reported that 7-8 hours of sleep is associated with the lowest risk…
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Prebiotics & Cognitive Function
Results of a randomized controlled trial performed to evaluate the effectiveness of a prebiotic supplement on both muscle function and cognition in a healthy older population were recently published in Nature Communications. To limit genetic confounding, this study was conducted among twins (monozygotic and dizygotic) and is known as the PRebiotic and PrOtein on Muscle…
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Vitamin D & CRP
A systematic review and meta-analysis recently published in the Journal of the Academy of Nutrition and Dietetics examined the effects of vitamin D supplementation in post-menopausal women on both blood pressure and C-reactive protein, a marker of systemic inflammation and cardiovascular disease risk. This analysis included 7 randomized and controlled trials, directly comparing the effects…
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Keto & Polycystic Kidney Disease
A study published recently in Cell Reports Medicine showed that a ketogenic diet is safe, feasible, and may be a beneficial intervention for patients with autosomal-dominant polycystic kidney disease (ADPKD), which is the most common genetic cause of kidney failure.