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Berberine’s Effect on the Glycemic Profile
Results of a randomized clinical trial were recently published in the European Review for Medical and Pharmacological Sciences, detailing the effect of berberine (as Berberine PhytosomeTM) on the metabolic profile of overweight participants with impaired fasting glucose (IFG). Forty-nine non-diabetic participants with a fasting glucose between 110 and 126 mg/dL and a mean BMI near…
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Berberine: The Gut-Brain-Heart Connection
Most of us have heard about the gut-brain connection, how nearly 90% of the body’s serotonin is actually made in the digestive tract, and how the gut-brain axis is the missing link in depression. Gut health and the landscape of the gut microbiota influence many aspects of our health, so it is no surprise that…
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Microbiome, Diabetes & Berberine
In October 2020, results were released from the PREMOTE (Probiotics and berberine on the efficacy and change of gut microbiota in patients with newly diagnosed type 2 diabetes) study. This multi-center, controlled trial had approximately 400 participants recently diagnosed with type 2 diabetes (drug naïve), randomized to one of 4 groups; probiotics + berberine, berberine + placebo, probiotics + placebo, or…
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Berberine and Blood Sugar
Berberine has become synonymous with supporting the maintenance of healthy blood sugar levels, as well as having benefits for the gut, brain and heart. A recent article delves into the biological mechanisms of this botanical to confirm its influence on blood sugar. Although not fully understood, the pathogenesis of Type 2 Diabetes Mellitus (T2DM) seems…